Radiosensitivity相关论文
Polygenic risk score for prediction of radiotherapy efficacy and radiosensitivity in patients with n
Objective:Toconstructanovelpolygenicriskscoringmodel,inordertopredictthebenefitsofradiosensitivityinpatientswithnon-meta......
Salicylic acid sensitizes cervical cancer cells to radiotherapy by activating AMPK/TSC2/mTOR pathway
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With the development of modern computing technology and medical physics, radiotherapy has made great progress. The theor......
ObjectiveLung cancer cells associated with radioresistance are likely to give rise to local recurrence and distant metas......
Histone deacetylase inhibitor, 2-propylpentanoic acid, increases the chemosensitivity and radiosensi
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ObjectiveTo study the nuclear protein association of high-mobility group box-1(HMGB1) and histone deacetylase 1(HDAC1), ......
目的研究下调lncRNA LINC00263靶向miR-4458对乳腺癌SK-BR-3细胞增殖、运动、侵袭及放射敏感性影响。方法qRT-PCR方法分别检测乳腺......
目的探索miR-205-5p/E2F1信号轴在脑胶质瘤U251、U87细胞放射耐受中的调控机制。方法利用X射线逐步递增递间歇诱导方法照射U251、U......
目的探究circ_0023990对甲状腺癌细胞放射敏感性的影响及可能机制。方法采用逆转录聚合酶链反应(qRT-PCR)法检测2016年8月至2018年11......
目的探究LncRNA BBOX1-AS1在卵巢癌(ovarian cancer,OC)放疗敏感性中的作用及潜在机制。方法qRT-PCR检测OC组织和细胞中BBOX1-AS1、mi......
目的探讨沉默FAM83D对X线照射后食管鳞状细胞癌(ESCC)细胞增殖、存活能力及侵袭、迁移能力的影响及机制。方法采用免疫组化法检测6......
目的探讨circ_0001955对前列腺癌DU145细胞系放射敏感性的影响及分子机制。方法将si-con、si-circ_0001955、miR-con、miR-149转染......
目的探讨Myosin X对肺癌H1975细胞系放射敏感性调节及相关机制。方法蛋白免疫印迹法检测肺癌细胞系中Myosin X表达量以获取实验对......
目的 探讨抑制miR-21表达对SHG-44人脑胶质瘤细胞系放射敏感性的影响及其机制.方法 脂质体介导采用瞬间转染法转染反义miR-21寡核......
目的 探讨LncRNA OIP5-AS1对非小细胞肺癌放射抗拒细胞A549R的放射敏感性影响及作用机制.方法 X射线6Gy照射5次A549细胞建立放射抗......
目的 探讨IncRNA GIHCG对胶质瘤细胞放射敏感性的影响及作用机制.方法 qRT-PCR实验检测人脑正常胶质细胞HEB和胶质瘤细胞系U251、A......
目的 观察反义表皮生长因子受体(EGFR)对人肺腺癌细胞系放射敏感性的影响.方法 在脂质体介导下用质粒pcDNA3-反义EGFR(pcDNA3-anti......
目的应用^60Coγ射线研究不同生存条件下恶性胶质瘤细胞株U251中肿瘤干细胞的放射敏感性。方法^60Coγ射线分别照射U251中的肿瘤干......
目的 将重组人外源性野生型p53(wtp53)基因的腺病毒转染人肺腺癌细胞系(A549),在乏氧状态下舰察wtp53基因对A549细胞照射后存活的......
脑胶质瘤是中枢神经系统最常见的肿瘤,其生长方式呈浸润性生长,手术中难以切除干净,易发生病灶残留从而引起术后复发,影响患者预后......
目的应用白藜芦醇作用于咽鳞癌细胞株FADU,观察其放疗增敏作用。方法体外培养咽鳞癌细胞株FADU,以细胞毒实验(cytotoxicity test,M......
目的探讨大蒜素(Allicin)是否能增加人皮肤基底细胞癌A431细胞的放疗敏感性及其作用机制。方法MTT法检测Allicin对A431细胞的生长......
放疗是头颈癌治疗的重要手段之一。头颈癌放疗敏感性受多种因素的影响,且机制各异。人乳头瘤病毒(human papillomavirus,HPV))感染,肿......
放疗是恶性胶质瘤最有效的治疗手段之一,然而,恶性胶质瘤具有显著的辐射抗性,虽然经过标准的放疗方案,恶性胶质瘤患者的预后仍差,......
目的探讨缺氧诱导因子-1α(HIF-1α)在高压氧(HBO)调控宫颈癌细胞放射敏感性中的作用及其机制。方法细胞培养完成后将宫颈癌Hela细......
目的探讨miR-199a-3p通过靶向结合p21蛋白激活激酶4(p21 protein activated kinase 4, PAK4)对胶质瘤U251细胞放疗敏感性的影响。......
siRNA-mediated silencing of Cockayne Cyndrome group B gene potentiates radiation-induced apoptosis a
Background Cockayne syndrome (CS) is a rare human genetic disorder characterized by increased UV sensitivity, developmen......
Histone deacetylase inhibitor, 2-propylpentanoic acid, increases the chemosensitivity and radiosensi
Background Treatment for malignant glioma generally consists of cytoreductive surgery followed by radiotherapy and chemo......
Silencing of osteopontin promotes the radiosensitivity of breast cancer cells by reducing the expres
Background Osteopontin (OPN) is a secreted phosphoglycoprotein (SSP) that is overexpressed in a variety of tumors and wa......
EGFR tyrosine kinase inhibitor HS-10182 increases radiation sensitivity in non-small cell lung cance
Objective: To investigate the potential of HS-10182, a second-generation epidermal growth factor receptor tyrosine kinas......
目的:探讨宫颈癌患者在同步放化疗中瘤体体积及其参数变化对预后的影响.方法: 回顾性分析217名接受根治性同步放化疗的宫颈癌患者.......
信号转导与转录激活因子3( STAT3)在多数肿瘤中处于过表达状态,其与肿瘤增殖、分化及凋亡密切相关,该信号通路激活能促进肿瘤的生长及......
目的:探讨自噬对人肺腺癌细胞放疗敏感性的影响。方法采用透射电镜和荧光显微镜检测亲本人肺腺癌细胞SPC?A1和耐药细胞SPC?A1/DTX放......
目的探讨尼妥珠单抗(h-R3)对体外人食管鳞癌KYSE30细胞株的放射增敏效应。方法采用培养的人食管鳞癌KYSE30细胞株行体外放射实验,......
Objective:To study the radiosensitivity of SiHa cells with Ku80 inhibition by RNAi.Methods:pKu80-siRNA and pNeg-siRNA we......
Relationship of HepG2 cell sensitivity to continuous low dose-rate irradiation with ATM phosphorylat
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Objective:To investigate whether the cell adhesion molecule integrin aV could influence the radiosensitivity of human na......
Predictive value of tumor volume reduction rates before and after induction chemotherapy in determin
Objective? This study investigated the predictive value of tumor volume reduction rates (TVRRs) before and after inducti......
Forty-six cases ofnasopharyngeal carcinoma treated with50Gy radiotherapy plushematoporphyrin derivat
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
DIFFERENCE IN BIOLOGICAL CHARACTERISTICS AND SENSITIVITY TO CHEMOTHERAPY AND RADIOTHERAPY BETWEEN IN
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Response of Lymphocytes to Radiation in Untreated Breast Cancer Patients as Detected with Three Diff
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Relationship of HepG2 cell sensitivity to continuous low dose-rate irradiation with ATM phosphorylat
Objective: To investigate the change of ATM phosphorylation in HepG2 cells and its effect on HepG2 cell survival under a......
Objective: To observe the radiosensitivity effect of AG825 on breast cancer cell line with high expression of ERBB2 in v......
Objective:To investigate whether the cell adhesion molecule integrin aV could influence the radiosensitivity of human na......
目的探讨宫颈癌组织中Ku80和ATM(毛细血管扩张性共济失调症突变蛋白,ataxia telangiectasia mutated)表达与放射敏感性的关系。方......
双链断裂是放射线引起的细胞致死性DNA损伤.细胞DNA双链断裂主要由同源重组和非同源末端连接两个分子途径进行修复.通过RNA干扰、......
目的探讨前列腺癌(PC)治疗前体外照射诱导的Go淋巴细胞微核量是否与放疗(xRT)相关疾病的发生有关.方法对38例PC周围血淋巴细胞(PBL......
目的 探讨PTEN基因敲除对辐射敏感性的影响及机制.方法 采用流式细胞术检测MEF1和MEF1/PTEN-/-细胞内ROS水平;采用Western blot方......